Education
Research Experience
Professional Experience
Hospital Appointments
Medical Licensure
Board Certification
Academic Awards
Membership in Societies
Basic Research
Clinical Research
Extramural Funding
Professional Activities
Visiting Professorships
Invited Lectures
Publications: Papers in Refereed Journals
Publications: Book Chapters
Publications: Abstracts and National and International Presentations
EDUCATION:
St. Paul Academy, 1966
St. Paul, Minnesota - High School Diploma
Rensselaer Polytechnic Institute, 1967
Troy, New York (Physics)
University of Minnesota - B.A., 1973
Minneapolis, Minnesota (Biology)
University of Minnesota - M.D., 1977
Minneapolis, Minnesota (Medicine)
University of Minnesota - Ph.D., 1989
Minneapolis, Minnesota (Surgery/Cell Biology)
Top of page
RESEARCH EXPERIENCE:
1967-1968 Undergraduate research in cell biology in the laboratory of Dr. Alan Hooper, UMN, Minneapolis, MN
1980-1983 Research Fellow in myocardial metabolism in the laboratory of Dr. John Foker, UMN, Minneapolis, MN
1988-1989 Research for and writing of doctoral thesis: Adenine nucleotide metabolism during myocardial ischemia and recovery.
Top of page
PROFESSIONAL EXPERIENCE:
1977-1978 Intern in Surgery, University of Minnesota (UMN), Minneapolis
1978-1980 Medical Fellow, Department of Surgery, UMN
1983-1985 Medical Fellow, Department of Surgery, UMN
1985-1988 Fellow, Thoracic and Cardiovascular Surgery, UMN
1988-1990 Instructor, Thoracic and Cardiovascular Surgery, UMN
1988-1990 Staff Surgeon, Thoracic and Cardiovascular Surgery, VA Medical Center (VAMC), Minneapolis, MN
1990-1994 Assistant Professor, Thoracic and Cardiovascular Surgery, UMN
1990-2007 Chief, Thoracic and Cardiovascular Surgery, VAMC
1992- Associate Member, Graduate Faculty, UMN
1994-1999 Associate Professor, Thoracic and Cardiovascular Surgery
1996-2007 Vice-Chief, Division of Thoracic and Cardiovascular Surgery, UMN
1996-2003 Associate Director, Fellowship Program, Division of Thoracic and Cardiovascular Surgery
1999- Professor, Thoracic and Cardiovascular Surgery, UMN
2007- C. Walton and Richard C. Lillehei Professor and Chief, Division of Cardiothoracic Surgery, UMN
Top of page
HOSPITAL APPOINTMENTS:
University of Minnesota Medical Center, Fairview
Minneapolis VA Medical Center
Regions Hospital
Fairview Southdale Medical Center
Top of page
MEDICAL LICENSURE:
Minnesota, 1977
Top of page
BOARD CERTIFICATION:
American Board of Surgery, 1987, recertified 1996
American Board of Thoracic Surgery, 1989, recertified 1998
Top of page
ACADEMIC AWARDS:
Magna cum laude - University of Minnesota
Lange Award - Senior Medical Student Academic Excellence
Phi Kappa Phi
NIH Traineeship Award
Minnesota Heart Association Young Investigator Award
Resident's Research Prize - Association for Academic Surgery
Top of page
MEMBERSHIP IN SOCIETIES:
American Association for Thoracic Surgery
American College of Cardiology (Fellow)
American College of Surgeons (Fellow)
American Heart Association, Council on Basic Science
American Heart Association, Council on Cardiopulmonary and Critical Care
Association for Academic Surgery
Association of VA Surgeons
Central Surgical Association
Lillehei Surgical Society
Phi Kappa Phi
Society of Thoracic Surgeons
Top of page
BASIC RESEARCH:
Energy preservation and myocardial hibernation. Co-principal Investigator.
Lipid and carbohydrate metabolism in post-ischemic myocardium using positron emission tomography and NMR. Principal investigator.
Purine metabolism, contractility and relaxation in post-ischemic myocardium. Principal investigator.
Top of page
CLINICAL RESEARCH:
VA Multicenter Cooperative study #474, Radial Artery vs Saphenous Vein in Coronary Artery Bypass Surgery, 2003-present, Co-investigator.
National VA Surgical Risk Study, 1988-present. Investigator.
VA Multicenter Cooperative Study #411, Coronary Artery Revascularization Prophylaxis Trial (CARP), 1997-2004. Co-principal Investigator.
VA Multicenter Cooperative Study #385, Urgent Revascularization in Unstable Angina (AWESOME), 1998-2000. Investigator
Prospective Randomized Multicenter Phase III Study Comparing Two Methods of Myocardial Protection in Coronary Bypass Surgery, 1998-1999. Investigator.
VA Multicenter Cooperative Study #5, Processes, Structures, and Outcomes of Care in Cardiac Surgery, 1994-1997. Investigator.
Top of page
EXTRAMURAL FUNDING:
VA Multicenter Cooperative Study #557, VA Coronary Artery Revascularization in Diabetes Study-“VA CARDS”, 2006-present, Co-Investigator.
Preconditioning effect within chronic hibernating myocardium. Minnesota Medical Foundation, 2004.
VA Multicenter Cooperative Study #474, Radial Artery vs Saphenous Vein in Coronary Artery Bypass Surgery, 2003-2008, Co-Investigator
Clinical Evaluation of Paracor Cardiac Support Device Therapy. Paracor Cardiovascular, Inc., 2002-present, Co-principal Investigator.
VA Multicenter Cooperative Study #385, Urgent Revascularization in Unstable Angina (AWESOME), 1998-2000, Investigator.
Coronary artery revascularization prophylaxis multicenter trial (CARP). A multicenter prospectively-randomized trial comparing myocardial revascularization with best medical therapy prior to peripheral vascular surgery. VA Cooperative Study, 1997-2004, Co-principal Investigator.
Effect of a ventricular diastolic restriction device in dogs with normal left ventricular function: Histologic and hemodynamic response. Acorn Medical, Inc., 1998, Principal Investigator.
Effect of a radiant-heat bandage on the healing of leg harvest wounds after coronary artery bypass grafting. Augustine Medical, Inc., 1998-1998, Co-principal Investigator.
Prospective randomized multicenter phase III study comparing two methods of myocardial protection in coronary bypass surgery. Koehler Chemie, 1998-1999. Investigator.
Purine metabolism, contractility and relaxation in post-ischemic myocardium. Minnesota Medical Foundation, 4/1/96-3/31/97, Principal Investigator.
Evaluation of Extracorporeal Blood Pump. Avecor Cardiovascular, 1995-1997, Principal Investigator.
VA Multicenter Cooperative Study #5, Processes, Structures, and Outcomes of Care in Cardiac Surgery, 1994-1997, Investigator.
Evaluation of the configuration and efficacy of an ultrasonic extravascular device (EDV) for monitoring cardiac output. Applied Biometrics, 1992-1993, Co-principal Investigator.
The effect of catecholamines on the ischemic myocardium. American Heart Association Grant-in-Aid Research Award, 1981-1983, Principal Investigator.
Adenosine metabolism and myocardial ischemia. National Heart, Lung and Blood Institute, National Research Service Award, 1980-1983, Principal Investigator.
Top of page
PROFESSIONAL ACTIVITIES:
Member, Cardiovascular Steering Committee, UMN, 2007-present.
Member, Critical Care Committee, UMN, 2007-present.
Member, Cardiovascular Performance Improvement Leadership Committee, UMN, 2007-present.
Member, VA Central Office Surgical Quality Data Use Group, 2006-present.
Member, Executive Committee, VA Multicenter Study #S57, VA Coronary Artery Revascularization in Diabetes - "VA CARDS," 2006-present.
Member, Board of Directors, Minnesota Society of Thoracic Surgeons, 2006-present.
Moderator, American Heart Association Abstract Oral Session: Surgical Treatment of Valve Disease, Chicago, IL, 2006.
Member, Search Committee for Chief, Cardiovascular and Thoracic Surgery, University of Minnesota, 2005-2007.
Member, VA Central Office Cardiac Surgery Consultant Board, 2003-present.
Chairman, Post-Tenure Review Committee, Department of Surgery, University of Minnesota, 2000-2002.
Member, Executive Committee, VA Multicenter Cooperative Study #411, Coronary Artery Revascularization Prophylaxis Trial (CARP), 1997-2004.
Member, Death Review Committee, VA Multicenter Cooperative Study #5, Processes, Structures, and Outcomes of Care in Cardiac Surgery, 1994-1997.
Elected Member, Department of Surgery Associates Management Committee, University of Minnesota, 1996-2002.
Peer Review Committee, American Heart Association, MN Affiliate, 1996-1997.
Member, Program Committee, Association for Academic Surgery, 1996-1997.
Co-Chair, Scientific Sessions, Association for Academic Surgery, Dallas, TX, 1997.
Co-Chair, Scientific Sessions, Association for Academic Surgery, Chicago, IL, 1996.
Member, Department of Surgery Research Council, University of Minnesota, 1995-1996.
Associate Examiner, American Board of Surgery, 1995.
Guest Reviewer:
Annals of Thoracic Surgery (1994-present)
Journal of Surgical Research (1995-present)
Chest (1995-present)
Journal of Laboratory and Clinical Medicine (1996-present)
American Journal of Cardiology (1996-present)
Circulation (2006-present)
Top of page
VISITING PROFESSORSHIPS:
University of Texas at San Antonio, TX, Surgery for Hypertrophic Obstructive Cardiomyopathy, August 21-22, 1997.
Top of page
INVITED LECTURES
St. Jude Symposium for Japanese Surgeons, Aortic Homografts. Minneapolis, MN, August 31, 1998.
American Association of VA Nurse Anesthetists. Hypertrophic obstructive cardiomyopathy. Minneapolis, MN, August 20, 1998
Cardiology Staff/Fellow Clinical Research Conference, Division of Cardiology, Department of Medicine, University of Minnesota. Hypertrophic obstructive cardiomyopathy. Minneapolis, MN, December 5 1996.
American Association of Critical Care Nurses. Valvuloplasty: Back to the future. Minneapolis, MN, April 18, 1994.
Rural Physician Associates Program. Thoracic Trauma. Fergus Falls, MN, March 26, 1994.
Cardiology Staff/Fellow Clinical Research Conference, Division of Cardiology, Department of Medicine, University of Minnesota. Valve repair and replacement. Minneapolis, MN, February 22, 1994.
Minnesota Surgical Society. The ivory tower from outside and in: A survey of Minnesota surgeons. St. Paul, MN, April 16, 1993.
Pulmonary Critical Care Research Conference, Division of Pulmonary Medicine, Department of Medicine, University of Minnesota. Critical care in the post-cardiopulmonary bypass patient. Minneapolis, MN, March 4, 1993.
Cardiology Staff/Fellow Clinical Research Conference, Division of Cardiology, Department of Medicine, University of Minnesota. Myocardial protection during open heart surgery. Minneapolis, MN, February 23, 1993.
Rural Physician Associates Program. Coronary artery surgery: An update. St. Peter, MN, April 7, 1992.
American Association of VA Nurse Anesthetists. Anesthesia for thoracoabdominal aneurysm repair. Minneapolis, MN, February 1, 1992.
Rural Physician Associates Program. Principles of chest trauma. Aitken, MN, April 16, 1991.
Surgical-Medical Clinics for Family Practice. Chest trauma. Brainerd, MN September 15, 1990.
American Association of VA Nurse Anesthetists Annual Meeting. Anesthesia for cardiac surgery: A surgeon's viewpoint. Minneapolis, MN, May 24, 1990.
National Association of Physician Assistants Annual Meeting. Cardiothoracic surgery and the Physician Assistant. Minneapolis, MN, April 28, 1990.
Rural Physician Associates Program. Coronary artery surgery: An update. Benson, MN, April 25, 1990.
Rural Physician Associates Program. Coronary artery surgery: An update. Benson, MN, April 25, 1990.
Rural Physician Associates Program. Evaluation of the solitary pulmonary nodule. Forest Lake, MN, January, 1989.
Surgical-Medical Clinics for Family Practice. Coronary artery surgery: An update. Brainerd, MN September 10, 1989.
Twin City Thoracic and Cardiovascular Society. Adenosine metabolism in the post-ischemic myocardium. St. Paul, MN, January, 1983.
Top of page
PUBLICATIONS: PAPERS IN REFEREED JOURNALS
1. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE: Enhanced regeneration of postischemia myocardial adenosine triphosphate concentrations. Surg Forum 32:254, 1981.
2. Ward HB, Einzig S, Wang T, Bianco RW, Foker JE: Enhanced cardiac efficiency with dobutamine after global ischemia. J Surg Res 33:32-8, 1982.
3. Ward HB, Einzig S, Bianco RW, Wang T, Foker JE: Effects of dopamine and dobutamine on the myocardial and systemic circulation during and following cardiopulmonary bypass in dogs. Ped Cardiol 3:257-64, 1982.
4. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE: Consequences of acute beta adrenergic blockage on myocardial ischemia during cardiopulmonary bypass. Current Surgery 40(2):106-14, 1983.
5. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE: Prevention of ATP catabolism during myocardial ischemia: A preliminary report. J Surg Res 34:292-7, 1983.
6. Ward HB, Kriett JM, Einzig S, Bianco RW, Anderson RW, Foker JE: Adenine nucleotides and cardiac function following global myocardial ischemia. Surg Forum XXXIV:264-6, 1983.
7. Ward HB, Einzig S, Wang T, Bianco RW, Foker JE: Comparison of catecholamine effects on myocardial metabolism and regional blood flow during and after cardiopulmonary bypass. J Thorac Cardiovasc Surg 87(3):452-65, 1984.
8. Ward HB, St. Cyr JA, Cogordann J, Alyono D, Bianco RW, Kriett JM, Foker JE: Recovery of adenine nucleotide levels following global myocardial ischemia in dogs. Surgery 96(2):248-55, 1984.
9. Ward HB, Ahrenholz DH, Crandall H, Solem LD: Primary closure of wounds in burned tissue: Experimental and clinical study. J Trauma 25(2):125-7, 1985.
10. St. Cyr JA, Ward HB, Kriett JM, Alyono D, Einzig S, Bianco RW, Anderson RW, Foker JE: Long term model for evaluation of myocardial metabolic recovery following global ischemia. Adv Exp Med Biol 194:401-14, 1986 (Review).
11. St. Cyr JA, Ward HB, Molina JE: Correction of thoracic aortic aneurysm--Bronchial fistula. J Cardiac Surg 2:109-13, 1987.
12. Becker W, Konstantinides F, Eyer S, Ward H, Fath J, Cerra F: Plasma amino acid clearance as an indicator of hepatic function and high-energy phosphate in hepatic ischemia. Surgery 102(5):777-83, 1987.
13. Ward HB, Pliego M, Diefenthal HC, Humphrey EW: The impact of CT scanning on surgery for the solitary pulmonary nodule. Surgery 106(4):734-9, 1989.
14. Molina JE, Edwards JE, Ward HB: Primary cardiac tumors: Experience at the University of Minnesota. Thorac Cardiovasc Surgeon 38:183-91, 1990.
15. Grover F, Hammermeister K, Burchfiel C and Cardiac Surgeons of the Department of Veterans Affairs: Initial report of the Veterans Affairs Preoperative Risk Study for Cardiac Surgery. Ann Thorac Surg 50:12-28, 1990.
16. Hammermeister KE, et al: Identification of patients at greatest risk of developing major complications at cardiac surgery. Circulation 82(Suppl IV):380-389, 1990.
17. McFalls EO, Duncker DJ, Krams R, Ward H, Gornick C, Verdouw PD: Endothelium dependent vasodilatation following brief ischaemia and reperfusion in anaesthetised swine. Cardiovasc Res 25:659-65, 1991.
18. Ward HB, Smith RA, Landis K, Nemzek T, Dalmasso A, Swaim W: A prospective randomized trial of autotransfusion after routine cardiac surgery. Ann Thorac Surg 56:137-41, 1993.
19. Ward HB, Macauley MK, Foker JE: The ivory tower from outside and in: A survey of Minnesota surgeons. Surgery 114:436-41, 1993.
20. Slaughter M, Olson M, Lee JT, Ward HB: A fifteen year continuous wound surveillance study in patients following coronary artery bypass. Ann Thorac Surg 56:1063-8, 1993.
21. Grover FL, Johnson R, Marshall G, Hammermeister KE and Department of Veterans Affairs Cardiac Surgeons: Factors predictive of operative mortality among coronary artery bypass subsets. Ann Thorac Surg 56:1296-1307, 1994.
22. Grover FL, Johnson R, Marshall G, Hammermeister KE and Department of Veterans Affairs Cardiac Surgeons: Impact of mammary grafts on coronary bypass operative mortality and morbidity. Ann Thorac Surg 57:559-569, 1994.
23. Hammermeister KE, Johnson R, Marshall G, Grover FL, Department of Veterans Affairs Cardiac Surgery Consultant Committee, Department of Veterans Affairs Cardiac Surgeons: Continuous assessment and improvement in quality of care: A model from the Department of Veterans Affairs Cardiac Surgery. Ann Surg 219:1-10, 1994.
24. McFalls EO, Ward HB, Fashingbauer P, Palmer B: The effects of dobutamine stimulation on regional myocardial glucose uptake poststunning as measured by positron emission tomography. Cardiovasc Res, 28:1030-1035, 1994.
25. Macpherson DS, Parenti C, Nee J, Petzel RA, Ward H: An internist joins the surgery service: Does comanagement make a difference? J Gen Intern Med 9:440-444, 1994.
26. McFalls EO, Ward H, Fashingbauer P, Gimmestad G, Palmer B: Myocardial blood flow and FDG retention within acutely stunned porcine myocardium. J Nuc Med 36(4):637-643, 1995.
27. Baldwin D, McFalls E, Archer S, Jaimes D, Fashingbauer P, Nemzek T, Purrington J, Ward H: Functional and metabolic effects of regional ischemic preconditioning on global myocardial ischemia. Surg Forum 46:214-216, 1995.
28. Ward HB, Chesler E: Surgical repair for severe mitral valve prolapse and regurgitation in elderly men. Cardiovasc Rev Report 16(12):23-25, 1995.
29. McFalls EO, Duncker DJ, Ward H, Fashingbauer P: Impaired endothelium-dependent vasodilation of coronary resistance vessels in severely stunned porcine myocardium. Basic Res Cardiol, 90:498-506, 1995.
30. McFalls EO, Ward H: FDG uptake within regionally stunned myocardium. Am J Card Imag, 9:269-274, 1995.
31. Ward HB, McFalls, EO, Baldwin D, Nemzek TG, Gornick CC: Cardiopulmonary support mitigates the effects of experimental myocardial ischemia. Chest 109:773-779, 1996.
32. Baldwin DR, McFalls EO, Jaimes D, Fashingbauer P, Nemzek T, Ward HB: Myocardial glucose metabolism and ATP levels are decreased two days after global ischemia. J Surg Res 63:35-38, 1996.
33. Baldwin D, Chandrashekhar Y, Liu D, Jaimes D, McFalls E, Anand I, Ward H: Myocyte response to calcium following reversible ischemia is preserved by ischemic preconditioning. Surg Forum, 47:239-40, 1996.
34. McFalls EO, Baldwin D, Marx D, Fashingbauer P, Ward H: Temporal changes in function and regional glucose uptake within stunned porcine myocardium. J Nuc Med 37(12):2006-10, 1996.
35. McFalls EO, Baldwin D, Palmer B, Marx D, Jaimes D, Ward HB: Regional glucose uptake within hypoperfused swine myocardium as measured by positron emission tomography. Am J Physiol 272:H343-H349, 1997.
36. Sechriest VF, Jaklitsch MT, Ward HB, Santilli SM: Symptomatic coronary-subclavian steal syndrome: a case report of successful management with carotid to subclavian artery bypass. Surg Rounds 20:167-172, 1997.
37. Baldwin DR, Slaughter MS, Park S, McFalls E, Ward HB: Coronary bypass grafting for single vessel coronary artery disease: A 17 year review with short and long term follow-up. Chest 113:676-680, 1998.
38. McFalls EO, Ward HB, Scheftel M, Chesler E, Doliszny KM: The influence of perioperative myocardial infarction on long-term prognosis following elective vascular surgery. Chest 113:681-686, 1998.
39. Baldwin D, McFalls E, Jaimes D, Marx D, Nemzek T, Ward HB: Adenosine protects high energy phosphate levels and glucose metabolism prior to reversible myocardial ischemia. Appl Cardiopulm Pathophys 7:41-46, 1998.
40. Ward HB, Baldwin DR, Wang T, Warner H, Seymour K, Marquardt C, McFalls E, Foker JE: Ion-exchange column chromatographic method for assaying purine metabolic pathway enzymes. J Chromatogr B 707:295-300, 1998.
41. McFalls EO, Baldwin D, Marx D, Jaimes D, Fashingbauer P, Ward HB: Adenosine receptor blockade enhances myocardial stunning without a sustained effect on fluorine-18-FDG uptake postreperfusion. J Nucl Med 39:944-949, 1998.
42. McFalls EO, Ward HB: Flow-metabolism mismatch and severe ischemic cardiomyopathy. Circulation 98:2218, 1998.
43. McFalls EO, Ward HB, Krupski WC, Goldman S, Littooy F, Eagle K, Nyman JA, Moritz T, McNabb, S, Henderson WG: Prophylactic coronary artery revascularization for elective vascular surgery: Study design. Controlled Clinical Trials, 20:297-308, 1999.
44. McFalls EO, Baldwin D, Marx D , Fashingbauer P, Ward HB: Effect of regional hyperemia on myocardial uptake of 2-deoxy-2-[18F]-fluoro-D-glucose. Am J Physiol Endocrinol Metab, 278:E96-E102, 2000.
45. McFalls EO, Baldwin DR, Marx D, Maxwell K, Ward HB: Glucose uptake increases relative to oxygen consumption during short-term hibernation. Basic Res Cardiol 95(1):39-46, 2000.
46. McFalls EO, Baldwin D, Kuskowski M, Liow J, Chesler E, Ward HB: Utility of positron emission tomography in predicting improved left ventricular ejection fraction after coronary artery bypass grafting among patients with ischemic cardiomyopathy. Cardiol 93(1-2):105-112, 2000.
47. Baldwin DR, Chandrashekhar Y, McFalls EO, Anand I, Liu D, Marx D, Ward HB: Ischemic preconditioning prior to aortic cross-clamping protects high-energy phosphate levels, glucose uptake and mocyte contractility. J Surg Research 105:153-159, 2000.
48. McFalls EO, Murad B, Liow JS, Gannon MC, Haspel HC, Lang A, Marx D, Sikora J, Ward HB: Glucose uptake and glycogen levels are increased in pig heart after repetitive ischemia. American Journal of Physiology 282:H205-H211, 2002.
49. Morrison DA, Sethi G, Sacks J, Henderson WG, Grover F, Sedlis S, Esposito R, Investigators of the Department of Veterans Affairs Cooperative Study #385, angina with Extremely Serious Operative Mortality Evaluation: Percutaneous coronary intervention versus repeat bypass surgery for patients medically refractory myocardial ischemia: AWESOME randomized trial and registry experience with post-CABG patients. J AM Coll Cardiol 40:1951-1954, 2002.
50. Sedlis SP, Morrison DA, Lorin JD, Esposito R, Sethi G, Sacks J, Henderson W, Grover F, Ramanathan KB, Weiman D, Saucedo J, Antakli T, Paramesh V, Pett S, Vernon S, Birjiniuk V, Welt F, Krucoff M, Wolfe W, Lucke JC, Mediratta S, Booth D, Murphy E, Ward H, Miller L, Kiesz S, Barbiere C, Lewis D; Investigators of the Dept. of Veterans Affairs Cooperative Study #385, the Angina with Extremely Serious Operative Mortality Evaluation (AWSOME): Percutaneous coronary intervention versus coronary bypass graft surgery for diabetic patients with unstable angina and risk factors for adverse outcomes with bypass: outcome of diabetic patients in the AWESOME randomized trial and registry. J Am Coll Cardiol 40:1555-1566, 2002.
51. Rumsfeld JS, Magid DJ, Plomondon ME, Sacks J, Henderson W, Hlaatky M, Sethi G, Morrison DA, for the Department of Veterans Affairs Agina with Extremely Serious Operative Mortality (AWESOME) Investigators: Health-related quality of life after percutaneous coronary intervention versus coronary bypass surgery in high-risk patients with medically refractory ischemia. J Am Coll Cardiol 41:1732-1738, 2003.
52. McFalls EO, Murad B, Her D, Liow J-S, Kelly R, Marx D, Sikora J, Ward HB: Repetitive supply-demand ischemia with dobutamine increases glucose uptake in postischemic and remote myocardium. J Nucl Med 44:85-91, 2003.
53. Bittner HB, Savitt MS, Ching PV, Ward HB: Off-pump coronary artery revascularization: ideal indication for patients with porcelain aorta and calcification of great vessels. J Cardiovasc Surg (Torino) 44:217-221, 2003.
54. McFalls EO, Murad B, Haspel HC, Marx D, Sikora J, Ward HB: Myocardial gluose uptake after dobutamine stress in chronic hibernating swine myocardium. J Nucl Cardiol 10:385-397, 2003.
55.O'Brien MM, Shroyer AL, Moritz TE, London MJ, Grunwald GK, Villanueva CB, Thottapurathu LG, MaWhinney S, Marshall G, Grover FL, Hammermeister KE, for the Participants of the VA Cooperative Study Group on Processess, Structures, and Outcomes of Care in Cardiac Surgery: Relationship between processes of care and coronary bypass operative mortality and morbidity. Med Care 42:59-70, 2004.
56. Adabag AS, Dykoski R, Ward H, Anand IS: Critical stenosis of aortic and mitral valves after mediastinal irradiation. Catheter Cardiovasc Interv 63:247-250, 2004.
57. Ward HB, Kelly RF: OPCAB versus CABG: Who, what, when, where? (editorial). Chest 125:815-816, 2004.
58. Pierpont GL, Moritz TE, Goldman S, Krupski WC, Littooy F, Ward HB, McFalls EO and the current . Disparate opinions regarding indications for coronary artery revascularization prior to elective vascular surgery. Am J Cardiol, 94:1124-1128, 2004.
59. McFalls EO, Hu M, Bache RJ, Best A, Marx D, Sikora J, Ward HB: Activation of p38 MAPK and increased glucose transport in chronic hibernating swine myocardium. Am J Physiol Heart Circ 287:H1328-H1334, 2004.
60. McFalls EO, Ward HB, Moritz TE, Goldman S, Krupski WC, Littooy F, Pierpont G, Santilli S, Rapp J, Hattler B, Shunk K, Jaenicke C, Thottapurathu L, Ellis N, Reda DJ, Henderson WG: Coronary artery revascularization prior to major elective vascular surgery does not improve outcome: The coronary artery revascularization prophylaxis (CARP) Trial. NEJM 351:2795-2804, 2004.
61. Sedlis SP, Ramanathan KB, Morrison DA, Sethi G, Sacks J, Henderson W for the Investigators of the Departmen of Veterans Affairs Cooperative Study #385, the Angina With Extremely Serious Operative Mortality Evaluation (AWESOME). Outcome of percutaneous coronary intervention versus coronary bypass grafting for patients with low left ventricular ejection fractions, unstable angina pectoris, and risk factors for adverse outcomes with bypass (the AWESOME Randomized Trial and Registry). Am J Cardiol 2004; 94:118-20.
62. Raghunathan A, Rapp JH, Littooy F, Santilli S, Krupski WC, Ward HB, Thottapurathu L, Mortiz T, McFalls EO. Post-operative outcomes for patients undergoing elective revascularization for critical limb ischemia and intermittent claudication: A subanalysis of the Coronary Artery Revascularization Prophylaxis (CARP) trial. J Vasc Surg 2006; 43(6):1175-82.
63. Ward HB, Kelly RF, Moritz TE, Thottapurathu L, McFalls EO: Perioperative myocardial infarction following vascular surgery and the completeness of preoperative coronary artery revascularization with CABG versus PCI: The Coronary Artery Revascularization Prophylaxis (CARP) Trial. Ann Thor Surg, 2006; 82:795-801.
64. McFalls EO, Wluiter W, Schoonderwoerd K, Manintveld OC, Lamers JMJ, Bezstarosti K, van Beusekom H, Sikora J, Ward HB, Merkus D, Duncker DJ. Mitochondrial adaptations within chronically ischemic swine myocardium. J Mol Cell Cardiol 2006; 41:980-8.
65. Adabag AS, Rector T, Harmala J, Ward HB, Kelly RF, Nguyen JT, McFalls EO, Bloomfield HE: Prognostic significance of elevated cardiac troponin I after heart surgery. Ann Thor Surg 2007;83:1744-50.
66. McFalls EO, Kelly RF, Hu Q, Mansoor A, Lee J, Kuskowski M, Sikora J, Ward HB, Zhang J. The energetic state within hibernating myocardium is normal during dobutamine despite inhibition of ATP-dependent potassium channel opening with glibenclamide. Am J Physiol Heart Circ Physiol. 2007. Nov;293(5):H2945-51. Epub 2007 Aug 24.
67. McFalls EO, Ward HB, Moritz TE, Littooy F, Santilli S, Rapp J, Larsen G, Reda DJ. Clinical factors associated with long-term mortality following vascular surgery: outcomes from the Coronary Artery Revascularization Prophylaxis (CARP) Trial. J Vasc Surg. 2007 Oct;46(4):694-700.
Top of page
PUBLICATIONS: BOOK CHAPTERS
1. St. Cyr JA, Ward HB, Kriett JM, Alyono D, Einzig S, Bianco RW, Anderson RW, Foker JE: Long term model for evaluation of myocardial metabolic recovery following global ischemia. In: Brautbar, N. (ed), Myocardial and Skeletal Bioenergetics. New York, NY, Plenum Publishing, 1986, pp. 401-14.
2. Ward HB, Andreone PA: Cardiac surgery. In: Chesler, E. (ed), Clinical Cardiology in the Elderly, New York, NY, Futura Publishing, 1994, pp. 213-231.
3. Humphrey EW, Ward HB, Perri RT: Lung cancer. In: Murphy GP, Lawrence Jr W, Lenhard Jr RE (eds), American Cancer Society Textbook of Clinical Oncology, Second Edition, Chapter 13, pp. 220, 1995.
4. Santamarina L, Ward HB: Cardiac surgery. In: Chesler, E. (ed), Clinical Cardiology in the Elderly, 2nd Edition, New York, NY, Futura Publishing, 1999, pp. 645-64.
5. Slaughter MS, Ward HB: Surgical management of heart failure. In: Rich MW (ed), Clinics in Geriatric Medicine, Philadelphia, WB Saunders Company, 16(3):567-592, 2000.
Top of page
PUBLICATIONS: ABSTRACTS AND NATIONAL AND INTERNATIONAL PRESENTATIONS
1. Einzig S, Foker JE, Ward HB, Bianco RW, Borgwardt B, Wang T: Effect of dopamine and dobutamine on regional blood flow, myocardial oxygen consumption and high energy phosphate compounds during cardiopulmonary bypass. Am J Cardiol 47:416, 1981.
2. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE: Enhanced regeneration of postischemia myocardial adenosine triphosphate concentrations. American College of Surgeons, Forum XXXII, San Francisco, CA, October, 1981.
3. Ward HB, Einzig S, Wang T, Bianco RW, Foker JE: Enhanced cardiac efficiency with dobutamine after global ischemia. Association for Academic Surgery, Chicago, IL, November, 1981.
4. Foker JE, Wang T, Ward HB, Bianco RW, Einzig S: Role of myocardial 5'-nucleotidase in the control of adenosine catabolism following ischemia. Am J Cardiol 49:1014, 1982.
5. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE: Consequences of acute beta adrenergic blockage on myocardial ischemia during cardiopulmonary bypass. Twenty-Fourth Annual University Surgical Residents Conference, New York, NY, February, 1982.
6. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE: Prevention of ATP catabolism during myocardial ischemia: A preliminary report. Association for Academic Surgery, San Diego, CA, November, 1982.
7. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE: Enhanced myocardial ATP recovery following ischemia with enzyme inhibition and precursor infusion. J Am Coll Cardiol 1(2):666, 1983.
8. Kriett JM, Ward HB, Bianco RW, Einzig S, Alyono D, Anderson RW, Foker JE: Recovery of adenine nucleotides and cardiac function following ischemia. Circulation 68(III):389, 1983.
9. Ward HB, Kriett JM, Einzig S, Bianco RW, Anderson RW, Foker JE: Adenine nucleotides and cardiac function following global myocardial ischemia. American College of Surgeons, Forum XXXIV, Atlanta, GA, October, 1983.
10. Ward HB, Kriett J, St. Cyr JA, Alyono D, Einzig S, Bianco RW, Anderson RW, Foker JE: Relationship between recovery of myocardial ATP levels and cardiac function following ischemia. J Am Coll Cardiol 3(2):544, 1984.
11. Foker JE, Ward HB, St. Cyr JA, Alyono D, Bianco RW, Kriett JM: Enhanced ATP return after global ischemia. Eur Heart J 5:91, 1984.
12. Ward HB, St. Cyr JA, Cogordann J, Alyono D, Bianco RW, Kriett JM, Foker JE: Recovery of adenine nucleotide levels following global myocardial ischemia in dogs. The 45th Annual Meeting of the Society of University Surgeons, Chicago, IL, February, 1984.
13. Ward HB, Ahrenholz, DH, Crandall H, Solem LD: Primary closure of wounds in burned tissue: Experimental and clinical study. American Burn Society Association Meeting, San Francisco, CA, April, 1985.
14. Becker W, Konstantinides F, Eyer S, Ward H, Fath J, Cerra F: Correlation of hepatic high energy phosphate (HEP) and plasma amino acid clearance (PAAC) in hepatic anoxia. Circulatory Shock, June, 1986.
15. Bankey PE, Ward HB, Eyer SD, Becker W, Cerra FB: Survival after reversible hepatic anoxia depends on the carbohydrate source. Crit Care Med 15(4):449, 1987.
16. Bankey P, Ward H, Eyer S, Becker W, Konstantinides F, Cerra F: Ribose affects mortality after reversible hepatic anoxia. Circulatory Shock 21(4):357, 1987.
17. Ward HB, Pliego M, Diefenthal HC, Humphrey EW: The impact of phantom CT scanning on surgery for the solitary pulmonary nodule. Central Surgical Association, Banff, Alberta, March, 1989.
18. Ward HB, Nemzek TG, McFalls EO, Gornick CC: Emergent cardiopulmonary bypass for acute myocardial ischemia in dogs. Circulation 84(Suppl III):681, 1990.
19. Andreone P, Ward HB, Humphrey EW: Twelve year experience with transthoracic and transhiatal esophagogastrostomies for esophageal cancer. Minnesota Surgical Society, Duluth, MN, September, 1991.
20. Andreone PA, Archer SL, Ward HB: Transesophageal echocardiography positively influences the development of a mitral valve repair program. Presented at the Association of VA Surgeons annual meeting, Albuquerque, NM, April, 1992.
21. Andreone P, Robinson C, Ward HB: Assuring quality of care through preoperative risk assessment in cardiac surgery at the Minneapolis VA Medical Center. Minnesota Surgical Society, Rochester, MN, April, 1992.
22. Kshettry VR, Ward H, Bolman III RM. Risk assessment and management of patients with left ventricle dysfunction undergoing CABG. Presented at the International Symposium on Cardiovascular Diseases. Bratislava, Czechoslovakia, September, 1992.
23. Kshettry VR, Ward H, Archer S, Bolman III RM. Use of transesophageal echocardiogram in mitral valve repair surgery. Presented at the Internal Symposium on Cardiovascular Diseases. Bratislava, Czechoslovakia, September, 1992.
24. McFalls EO, Duncker DJ, Ward H, Gornick CG, Fashingbauer P, Krieser M: In vivo evidence of altered endothelium-dependent vasodilation in stunned porcine myocardium. American Heart Association, New Orleans, LA, November, 1992.
25. Schiller L, Ward H, Archer S, Nelson D, Weir EK: Endothelial dysfunction in a canine model of high flow pulmonary hypertension. Am Rev Resp Dis 147:A497, 1993.
26. Slaughter M, Olson M, Lee JT, Ward HB: A fifteen year continuous wound surveillance study in patients following coronary artery bypass. Presented at the Society of Thoracic Surgeons annual meeting, San Antonio, TX, January, 1993.
27. Ward HB, Macauley MK, Foker JE: The ivory tower from outside and in: A survey of Minnesota surgeons. Presented at the Society of University Surgeons annual meeting, Seattle WA, February, 1993.
28. McFalls EO, Ward H, Fashingbauer P, Palmer B: FDG uptake in acutely stunned porcine myocardium is lower than remote regions despite recruitment of function and MVO2. Circulation (abstract 1060) 88(Suppl II):I-199, 1993
29. McFalls E, Ward H, Gimmestad G, Dant V: FDG uptake increases within chronically hibernating myocardium. Circulation (abstract 1686) 90(Suppl II):I-313, 1994.
30. McFalls E, Ward H, Fashingbauer P, Gimmestad G: Adenosine increases glucose uptake and decreases FDG retention within regional swine myocardium. Circulation (abstract 404) 90(Suppl II):I-76, 1994.
31. Baldwin D, McFalls E, Archer S, Jaimes D, Fashingbauer P, Nemzek T, Purrington J, Ward H: Functional and metabolic effects of regional ischemic preconditioning on global myocardial ischemia. Presented at the American College of Surgeons annual meeting, New Orleans, LA, October, 1995.
32. Baldwin DR, McFalls EO, Jaimes D, Fashingbauer P, Nemzek T, Ward HB: Myocardial glucose metabolism and ATP levels are decreased two days after global ischemia. Presented at the Association for Academic Surgery annual meeting, Dearborn, MI, November, 1995.
33. Baldwin D, Chandrashekhar Y, Ward H, Liu D, Anand I: Intermittent ischemia prior to prolonged reversible ischemia protects canine myocyte contractility. Presented at the American College of Cardiology annual meeting, Orlando, FL, 1996.
34. Ward, HB: The use of positron emission tomography for basic and clinical research in ischemic cardiomyopathies. Presented at the Central Surgical Association annual meeting, Minneapolis, MN, March 1996.
35. Baldwin D, Chandrashekhar Y, Liu D, Jaimes D, McFalls E, Anand I, Ward H: Myocyte response to calcium following reversible ischemia is preserved by ischemic preconditioning. Presented at the American College of Surgeons annual meeting, San Francisco, CA, October 1996.
36. McFalls EO, Baldwin DR, Marx D, Jaimes D, Ward HB: Dobutamine recruits perfusion within chronically ischemic myocardium. Presented at the American Heart Association annual meeting, New Orleans, LA, November 1996.
37. Baldwin DR, McFalls EO, Jaimes D, Nemzek T, Marx D, Ward HB: Adenosine pretreatment preserves glucose uptake and high energy phosphate levels at two days following reversible ischemia. Presented at the American Heart Association annual meeting, New Orleans, LA, November 1996.
38. Jaklitsch MT, Sechriest VF, Ward HB, Foker JE: Twenty year experience with peripheral radial plication of the diaphragm. Presented at the Society of Thoracic Surgeons, February 1997.
39. McFalls EO, Baldwin DR, Marx D, Jaimes D, Ward HB: The effect of maximal vasodilation on regional myocardial uptake of [18F]fluorodeoxyglucose. Circulation 96(8)I-625, 1997.
40. McFalls EO, Baldwin DR, Marx D, Jaimes D, Ward HB: The effects of repetitive stunning on regional myocardial glucose uptake in swine. Circulation 96(8): I-222, 1998.
41. McFalls EO, Marx D, Jaimes D, Liow J-S, Ward HB: The relationship between reduced flow reserve and enhanced glucose uptake within chronically ischemic myocardium. Circulation 98(17), I-222, 1998.
42. Chen K, Liow J, Lawson, M, Reiman E, Bandy D, McFalls EO, Ward H: The use of segmented attenuation correction method in quantitative N-13 ammonia PET myocardial perfusion studies. J Nuc Med 40:296, 1999.
43. McFalls EO, Baldwin D, Liow JS, Marx D, Ward H: Glucose transport and GLUT-4 content within chronically ischemic myocardium. J Am Coll Cardiol 35:479a, 2000.
44. McFalls EO, Haspel H, Lange A, Ward H: Myocardial glycogen and glucose uptake are increased post-repetitive ischemia-reperfusion. FASEB 14:A418, 2000.
45. McFalls EO, Marx D, Sikora J, Haspel H, Ward H: Hexokinase activity but not GLUT4 content is increased in repetitively ischemic-reperfused swine hearts. Circulation 102(18):II-578, 2000.
46. McFalls EO, Kelly R, Marx D, Sikora J, Ward H: Post-ischemic myocardial FDG uptake following repetitive coronary artery occlusion-reperfusion versus repetitive supply-demand mismatch. Circulation 104(17):II-455, 2001.
47. Baldwin D, Chandrashekhar Y, McFalls E, Anand I, Liu D, Jaimes D, Marx D, Ward H: Ischemic preconditioning prior to aortic cross-clamping protects high energy phosphate levels, glucose uptake, and myocyte contractility. J Am Coll Cardiol, 2002.
48. McFalls EO, Murad B, Marx D, Sikora A, Ward HB: The effects of p38 MAP kinase inhibition of creatine phosphate during moderate sustained regional myocardial ischemia. Circulation 106(19):II-196, 2002
49. Pierpont GL, Moritz TE, Goldman S, Krupski WC, Littooy F, Ward HB, McFalls EO: Disparate opinions regarding indications for coronary artery revascularization prior to elective vascular surgery. Presented at the American Heart Association scientific meeting, November 9, 2003, Orlando, FL.
50. McFalls EO, Hou MX, Bache RJ, Marx D, Sikora J, Ward HB: Activation of p38 MAP kinase is associated with increased glucose metabolism in chronic hibernating swine myocardium. Presented at the American Heart Association scientific meeting, November 9, 2003, Orlando, FL.
51. McFalls EO, Ward HB, Moritz TE, Goldman S, Krupski WC, Littooy F, Pierpont G, Santilli S, Rapp J, Hattler B, Shunk K, Jaenicke C, Thottapurathu L, Ellis N, Reda DJ, Henderson WG: Coronary artery revascularization prior to major elective vascular surgery does not improve outcome: The coronary artery revascularization prophylaxis (CARP) Trial. American Heart Association Late Breaking Trials, November 2004, New Orleans, LA.
52. Demmy TL, Ward HB, Gorton ME, Kouchoukos NT, Schmaltz RA, Shennib H, Molina JE. Custodiol® versus Plegisol® - A phase III multicenter myocardial preservation study. Society of University Surgeons, February 2005, Nashville, TN.
53 McFalls EO, Hu Q, Mansoor A, Lee J, Sikora J, Ward HB, Zhang J. The importance of ATP-dependent potassium channel opening to transmural energy in chronically ischemic swine myocardium. Circulation 2005; 112:II285.
54. McFalls EO, Ward HB, Moritz T, Goldman S, Pierpont G, Hattler B, Shrunk K, Larsen GC, Littooy F, Krupski W, Henerson W, Reda D. Perioperative myocardial infarction following elective vascular surgery: Clinical predictors and outcomes within the coronary artery revascularization prophylaxis (CARP) trial. Circulation 2005; 112:II707.
55. Khan A, Murad B, Sikora J, Ward HB, McFalls EO. Isolated mitochondria from preconditioned myocardium in the second window of protection are resistant to in vitro anoxia-reoxygenation. Circulation 2005; 112:II198.
56. McFalls EO, Ward HB, Moritz TE, Goldman S, Pierpont G, Santilli S, Rapp J, Hattler B, Shunk K, Fittooy F, Krupski WC, Henderson WG, Reda DJ. Perioperative myocardial infarction following elective vascular surgery: clinical predictors and outcomes with the Coronary Artery Revascularization Prophylaxis (CARP) Trial. Circulation 2005; 112:II-707.
57. Ward HB, Kelly RF, Moritz TE, Thottapurathu L, McFalls EO. Perioperative myocardial infarction following vascular surgery and the completeness of preoperative coronary artery revascularization with CABG versus PCI: The Coronary Artery Revascularization Prophylaxis (CARP) Trial. Society for Thoracic Surgery, January 2006, Chicago, IL.
58. Murray STN, Wassif HS, Moritz TE, Thottapurathu L, Pierpont G, Goldman S, Larsen TC, Ward HB, McFalls EO. Culprit coronary lesions requiring PCI following vascular surgery often arise from non-obstructive disease. American College of Cardiology, March 2007.
59. McFalls EO, Ward HB, Pierpont G, Wassif HS, Murray STN, Goldman S, Larsen GC, Littooy F, Krupski W, Moritz T, Reda D. Incidence of a left main stenosis among high risk patients presenting for elective vascular surgery and long-term outcomes. American College of Cardiology, March 2007.
60. McFalls EO, Ward HB, Peirpont G, Wassif HS, Murray STN, Goldman S, Larsen GC, Littooy F, Krupski W Moritz T, Reda D. Incidence of a left main stenosis among high risk patients presenting for elective vascular surgery and long-term outcomes. American College of Cardiology, March 2007.
61. Garcia S, Ward HB, Moritz T, Littooy F, Goldman S, Pierpont G, Larsen G, Reda D, McFalls E. Periopertive cardiac events following vascular surgery are predicted by the Revised Cardiac Index but are not reduced in any risk sub-group by preoperative coronary revascularization: results from the Coronary Artery Revascularization Prophylaxis (CARP) Trial. American College of Cardiology, March 2008, submitted.
Top of page
Return to: Medical School : Academic Health Center : myU : U of M Home
