Publications
Richard W. Bianco

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Publications (Peer Reviewed):

1. Josa M, Lie JT, Bianco RW, Kaye MP.  Reduction of thrombosis in canine coronary bypass vein grafts with dipyridamole and aspirin. Am J Cardiol 1981; 47 (6):1248-54.

2. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE. Enhanced regeneration of post-ischemia myocardial adenosine triphosphate concentrations.  Surg Forum. 1981;32:254.

3. Einzig S, Foker JE, Ward HB, Bianco RW, Borgwardt B, Wang T.  Effect of dopamine and dobutamine on regional blood flow, myocardial oxygen consumption and high energy phosphate compounds during cardiopulmonary bypass.  Am J Cardiol. 1981;47:416

4. Ward HB, Einzig S, Bianco RW, Wang T, Foker JE.  Effects of dopamine and dobutamine on the myocardial and systemic circulation during and following cardiopulmonary bypass in dogs. Pediatr Cardiol 1982; 3 (3):257-64.

5. Ward HB, Einzig S, Wang T, Bianco RW, Foker JE.  Enhanced cardiac efficiency with dobutamine after global ischemia. J Surg Res 1982; 33 (1):32-8

6. Foker JE, Wang T, Ward HB, Bianco RW, Einzig S.  Role of myocardial 5'-nucleotidase in the control of adenosine catabolism following ischemia. Am J Cardiol 1982; 49:1014.

7. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE.  Enhanced myocardial ATP recovery following ischemia with enzyme inhibition and precursor infusion.  J Am Coll Cardiol. 1983;1:666.

8. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE.  Consequences of acute beta adrenergic blockade on myocardial ischemia during cardiopulmonary bypass.  Current Surgery. 1983;40(2):106-10.

9. Ward HB, Wang T, Einzig S, Bianco RW, Foker JE.  Prevention of ATP catabolism during myocardial ischemia:  A preliminary report.  J Surg Res. 1983 Apr;34:292-7.

10. Ward HB, Kriett JM, Einzig S, Bianco RW, Andreson RW, Foker JE.  Adenine nucleotides and cardiac function following global myocardial ischemia.  Surg Forum. 1983;34:264-6.

11. Kriett JM, Ward HB, Bianco RW, Einzig S, Alyono D, Anderson RW, Foker JE.  Recovery of adenine nucleotides and cardiac function following ischemia.; Abstracts: 56th scientific sessions of the American Heart Association. November 14-17, 1983. Anaheim, California;. Circulation 1983; 68 (4 Pt 2):III 389.

12. Ward HB, Einzig S, Wang T, Bianco RW, Foker JE.  Comparison of catecholamine effects on canine myocardial metabolism and regional blood flow during and after cardiopulmonary bypass. J Thorac Cardiovasc Surg 1984; 87 (3):452-65.

13. Ward HB, St.Cyr JA, Cogordan JA, Alyono D, Bianco RW, Kriett JM, Foker JE.  Recovery of adenine nucleotide levels after global myocardial ischemia in dogs. Surgery 1984; 96 (2):248-55.

14. Ward HB, Kriett JM, St.Cyr JA, Alyono D, Bianco RW, Einzig S, Andreson RE, Foker JE.  Relationship between recovery of myocardial ATP levels and cardiac function following ischemia.; Abstracts of papers to be presented at the 33rd annual scientific session of the American College of Cardiology. Dallas, Texas, March 25-29, 1984; J Am Coll Cardiol 1984; 3 (2 Pt 2):544.

15. Molina JE, Einzig SE, Mastri AR, Bianco RW, Marks JA, Rasmussen TM, Clack RM.  Brain damage in profound hypothermia.  Perfusion versus circulatory arrest.  J Thorac Cardiovasc Surg. 1984 Apr;87(4):596-604.

16. Foker JE, Ward HB, St.Cyr JA, Alyono D, Bianco RW, Kriett JM.  Enhanced ATP return after global ischemia. IXth European Congress of Cardiology. Dusseldorf, 8th-12th July 1984. Abstracts;. Eur Heart J 1984; 5 Suppl 1:1-431.

17. St.Cyr JA, Bianco RW, Ascher NL, Foker JE.  Consequences of ischemia on organ energy metabolism. Proceedings of the Tenth International Congress of the Transplantation Society. August 26-31, 1984, Minneapolis, Minnesota. Transplant Proc 1985; 17 (1 Pt 2):1468.

18. Molina JE, Cogordan J, Einzig S, Bianco RW, Rasmussen T, Clack RM, Borgwardt B.  Adequacy of ascending aorta-descending aorta shunt during cross-clamping of the thoracic aorta for prevention of spinal cord injury. J Thorac Cardiovasc Surg 1985; 90 (1):126-36.

19. Einzig S, St.Cyr JA, Bianco RW, Schneider JR, Lorenz E, Foker JE.  Myocardial ATP repletion with ribose infusion. J Ped Res. 1985;19:127.

20. Fath J, St.Cyr JA, Konstantinides F, Alden P, Ascher N, Bianco RW, Foker J, Cerra FB.  Alterations in amino acid clearance during ischemia predict hepatocellular ATP changes. Surgery 1985; 98 (3):396-404.

21. Schneider JR, St.Cyr JA, Mahoney JR, Bianco RW, Ring WS, Foker JE.  Recovery of ATP and return of function after global ischemia; American Heart Association. Abstracts. 58th scientific sessions of the American Heart Association. November 11-14, 1985, Washington, D.C. Circulation 1985; 72 (4 Pt 2):IIIA-IIIH, III1-III597

22. St.Cyr J, Bianco R, Foker J, Noren G, Staley N, Wang Ting Chung, Einzig S.  Myocardial high energy phosphate levels in cardiomyopathic turkeys.  J Surg Res. 1986;41:256-9.

23. Bianco RW, St.Cyr JA, Schneider JR, Rasmussen TM, Clack RM, Shim HS, Sandstad J, Rysavy BA, Foker JE.  Canine model for long-term evaluation of prosthetic mitral valves.  J Surg Res. 1986 Aug;41:134-40.

24. Solis E, Tyce GM, Bianco R, Mahoney J, Kaye MP.  High energy phosphate and catecholamine store after prolonged ex vivo heart preservation. J Heart Transplantation. 1986;5(6):444-9.

25. St Cyr JA, Ward H, Kriett J, Alyono D, Einzig S, Bianco RW, Anderson R, Foker J. Long term model for evaluation of myocardial metabolic recovery following global ischemia. Adv Exp Med Biol 1986; 194:401-14.

26. St.Cyr J, Bianco R, Judd D, Pierpont M, Staley N, Noren G, Foker J, Einzig S.  A new method of urine collection in turkeys and chickens. Lab Anim Sci. 1987;37:366-7.

27. Tveter KJ, St.Cyr JA, Bianco RW, Einzig S, Foker JE.  Ribose enhanced recovery of diastolic function after myocardial ischemia. Ped Res. 1988;23:226A.

28. Tveter KJ, Bianco RW, Mahoney JR, Foker JE.  Ribose enhanced recovery of diastolic function after global myocardial ischemia. Circ. 1988;78(4):II-265.

29. St.Cyr J, Bianco RW, Schneider JR, Mahoney JR, Tveter K, Einzig S, Foker JE.  Enhanced high energy phosphate recovery with ribose infusion after global myocardial ischemia in a canine model. J. Surg Res 1989 Feb;46:157-62.

30. Molina JE, Edwards J, Bianco RW, Clack R, Rasmussen T, Moss G, Lang G, Physical and mechanical effects of cardioplegic injection on flow distribution and myocardial damage in hearts with normal coronary arteries. J Thorac Cardiovasc Surg 1989; 97 (6):870-7.

31. Molina JE, Galliani CA, Einzig S, Bianco RW, Rasmussen T, Clack R. Growth of fresh-frozen pulmonary allograft conduit in growing lambs. Circulation 1989; 80 (3 Pt 1):I183-90.

32. Robiatille PM, Merkle H, Sako E, Lang G, Clack RM, Bianco RW, From AHL, Foker JE, Ugurbil K.  Measurement of ATP synthesis rates by 31P-NMR Spectroscopy in the intact myocardium in vivo.  Magnetic Resonance in Medicine. 1990;15:8-24.

33. Irwin ED, Hendrich KR, Bianco RW, Ugurbil K, Foker JE.  Ischemia induced changes in energy regulation and capacity in the intact animal.; Abstracts from the 64th scientific sessions, American Heart Association. Anaheim, California, November 11-14, 1991; p. 856. Circulation 1991; 84 (4 Suppl):II1-894.

34. Silberbach M, Stejskal E, Foker JE, Bianco RW, Tobian L, Burnett JC Jr., Einzig S.  Newborn cardiorenal dynamics:  A state of atrial natriuretic peptide unresponsiveness.  Am J Physio. 1991;261(6 Pt 2);H2069-74.

35. Schoen FJ, Levy RT, Hilbert SL, Bianco RW.  Antimineralization treatments for bioprosthetic heart valves:  Assessment of efficacy and safety.  J Thorac Cardiovasc Surg. 1992 Nov;104(5):1285-8.

36. Gealow KK, Solien EE, Lang GR, Evanson CM, Bianco RW, Chiu RC, Shumway SJ.  Blood flow to the latissimus dorsi muscle pouch during chronic counterpulsation stimulation.  Journal Heart & Lung Trans. 1992 Sep-Oct;11(5):S306-14.

37. Gealow KK, Solien EE, Bianco RW, Chiu RCJ, Shumway SJ.  Effect of chronic stimulation on the blood flow and mechanics of a skeletal muscle ventricle.  Eur JCPE 1992;2(Supplement 1A):A198.

38. Irwin, ED, Clack R, Lang G, St. Cyr J, Runge W, Foker JE, Bianco RW.  Long-term evaluation of prosthetic mitral valves in sheep.  J  Invest Surg.  1993;6(2):133-41.

39. Gealow KK, Solien EE, Bianco RW, Chiu RCJ, Shumway SJ.  Conformational adaptation of muscle: implications in cardiomyoplasty and skeletal muscle ventricles.  Ann Thorac Surg. 1993 Sep;56(3):520-6.

40. Irwin ED, Bianco RW, Clack R, Grehan JF, Slovut DP, Nakhleh R, Bolman RM III, Shumway SJ.  Use of epicardial electrocardiograms for detecting cardiac allograft rejection.  Ann Thorac Surg. 1992 Oct;54(4):669-674; discussion 674-5.  Comment In: Ann of Thorac Surg. 1993;55(6):1593-4.

41. Gealow KK, Solien EE, Bianco RW, Shumway SJ.  Importance of adaptive stimulation of the latissimus dorsi muscle in cardiomyoplasty.  ASAIO J.  1994 Jul-Sep;40(3):M253-9.

42. Schoen FJ, Hirsch D, Bianco RW, Levy RJ.  Onset and progression of calcification in porcine aortic bioprosthetic valves implanted as orthotopic mitral valve replacements in juvenile sheep.  J Thorac Cardiovasc Surg. 1994 Nov;108(5):880-7.

43. Molina JE, Edwards JE, Bianco RW, Clack RW, Lang G, Molina JR.  Composite and plain tubular synthetic graft conduits in right ventricle-pulmonary artery position: fate in growing lambs.  Journal of Thoracic and Cardiovascular Surgery. 1995 Aug;110(2):427-35.

44. Gealow K, Solien EE, Bianco RW, Grandjean P.  Latissimus dorsi stimulation parameters for the prevention of muscle compromise in dynamic cardiomyoplasty.  Medtronic Science & Technology  1996;4(1):18-24,.

45. Bianco RW, Phillips R, Mrachek JP, Witson J.  Feasibility evaluation of a new pericardial bioprosthesis with dye mediated photo-oxidized bovine pericardial tissue.  The J Heart Valve Dis.  1996 May;5(3):317-22 .

46. Vyavahare N, Hirsch D, Lerner E, Baskin J, Schoen F, Bianco RW, Kruth H, Zand R, Levy R.  Prevention of bioprosthetic heart valve calcification by ethanol preincubation: efficacy and mechanism.  Circulation.  1997;95(2):479-88.  Comment in: Circulation. 1997;95(2): 297-8.

47. Gealow KK, Solien E, Bianco R, Grandjean PA.  Effect of adaptive pulse train duration on latissimus dorsi blood flow.  Artif Organs.  1997;21(3):243-6.

48. Tweden KS, Cameron JD, Razzouk AJ, Bianco RW, Holmberg WR, Bricault RJ, Barry JE, Tobin E.  Silver modification of polyethylene terephthalate textiles for antimicrobial protection.  ASAIO J 1997 Sep-Oct;43(5):M475-81.

49. Shake JG, Larson DW, Salerno CT, Bianco RW, Bolman III RM.  The role of electrolyte in lesion size using an irrigated radiofrequency electrode. J Invest Surg 1997 Nov-Dec;10(6):339-46; discussion 346-8

50. Salerno CT, Droel J, Bianco RW.  Current state of in vivo preclinical heart valve evaluation.  J Heart Valve Dis. 1998 Mar;7(2):158-62.

51. Lee CH, Vyavahare N, Zand R, Kruth H, Schoen FJ, Bianco RW and Levy RJ.  Inhibition of aortic wall calcification in bioprosthetic heart valves by ethanol pretreatment:  biochemical and biophysical mechanisms. J Biomedical Materials Research 1998 Oct;42 (1): 30-7.

52. Ouyang DW, Salerno CT, Pederson TS, Bolman III RM, Bianco RW.  Long-Term Evaluation of Orthotopically Implanted Stentless Bioprosthetic Aortic Valves in Juvenile Sheep. J Invest Surg 1998;11:175-83.

53. Salerno CT, Pederson TS, Ouyang DW, Bolman III RM, Bianco RW.  Chronic Evaluation of Orthotopically Implanted Bi-Leaflet Mechanical Aortic Valves in Adult Domestic Sheep.  J Invest Surg 1998;11 (5): 341-47.

54. Westaby S, Bianco RW, Katsumata T, Termin P.  The Carbomedics “Oxford” Photofix stentless valve (PSV). Semin Thorac Cardiovasc Surg. 1999 Oct;11(4 Suppl 1):206-9.

55. Illingworth B, Bianco RW, Weisberg S.  In vivo efficacy of silver-coated fabric against Staphylococcus epidermidis. J Heart Valve Dis. 2000 Jan;9(1):135-41.

56. Grehan JF,Hilbert SL, Ferrans VJ, Droel JS, Salerno CT, Bianco RW.  Development and Evaluation of a Swine Model to Assess the Preclinical Safety of Mechanical Heart Valves.  J. Heart Valve Dis. 2000 Sep;9(5): 710-9; discussion 719-20,

57. Cooper DM, McIver R, Bianco R.  The thin blue line:  a review and discussion of aseptic technique and postprocedural infections in rodents.  Contemp Top Lab Anim Sci. 2000 Nov;39(6):27-32

58. Svendsen CA, Kreykes NS, Butany J, Bianco RW.  In vivo assessment of a photofixed bovine pericardial valve. J. Heart Valve Dis. 2000 Nov;9(6):813-20,  discussion 820-1

59. Grehan JF, Casagrande I, Oliveira EL, Santos PC, Pessa CJ, Gerola LR, Buffolo E, Mrachek J, Norris ME, Lahti MT, Bianco RW.  A juvenile sheep model for the long-term evaluation of stentless bioprosthesis implanted as aortic root replacements.  J Heart Valve Dis. 2001 Jul;10(4):505-12

60. Alferiev I, Vyavahare N, Song C, Connolly J, Hinson JT, Lu Z, Tallapragrada S, Bianco RW, Levy R.  Bisphosphonate Derivatized Polyurethanes Resist Calcification. Biomaterials 2001;22:2683-93

61. Shake JG, Larson DW, Kulick DM, Salerno CT, Bianco RW, Bolman RM 3rd  Transmural atrial insulating lesions using epicardially applied radiofrequency energy coupled with saline irrigation., J Invest Surg. 2002 Mar-Apr;15(2):101-7.

62. Alferiev I, Stachelek SJ, Lu Z, Fu AL, Sellaro TL, Connolly JM, Bianco RW, Sacks MS, Levy RJ.  Prevention of polyurethane valve cusp calcification with covalently attached bisphosphonate diethylamino moieties. J Biomed Mater Res 2003; 66A (2):385-95.

63. Levy RJ, Vyavahare N, Ogle MF, Ashworth P, Bianco RW, Schoen FJ.  Inhibition of cusp and aortic wall calcification in ethanol- and aluminum-treated bioprosthetic heart valves in sheep: background, mechanisms, and synergism. J Heart Valve Dis 2003; 12 (2):209-16; discussion 16.

64. Ogle MF, Kelly SJ, Bianco RW, Levy RJ. Calcification resistance with aluminum-ethanol treated porcine aortic valve bioprostheses in juvenile sheep. Ann Thorac Surg 2003; 75 (4):1267-73.

65. Linden BC, Schumacher CW, MacIver RH, Mrachek JP, Bianco RW.  Paravalvular leaks around prosthetic valves implanted in the mitral position: technical refinements of the ovine model. J Heart Valve Dis 2003; 12 (3):400-5.

66. Fukamachi K, Inoue M, Popovic ZB, Doi K, Schenk S, Nemeh H, Ootaki Y, Kopcak MW, Jr., Dessoffy R, Thomas JD, Bianco RW, Berry JM, McCarthy PM.  Off-pump mitral valve repair using the Coapsys device: a pilot study in a pacing-induced mitral regurgitation model. Ann. Thorac. Surg. 2004; 77 (2):688-92.

67. Stachelek SJ, Song C, Alferiev I, Defelice S, Cui X, Connolly JM, Bianco RW, Levy RJ.  Localized gene delivery using antibody tethered adenovirus from polyurethane heart valve cusps and intra-aortic implants. Gene Ther 2004; 11 (1):15-24.

68. Rickers C, Gallegos R, Seethamraju RT, Wang X, Swingen C, Jayaswal A, Rahrmann EP, Kastenberg ZJ, Clarkson CE, Bianco RW, O'Brian T, Verfaillie C, Bolman RM, Wilke N, Jerosch-Herold M.  Applications of Magnetic Resonance Imaging for Cardiac Stem Cell Therapy. Journal of Interventional Cardiology 2004; 17 (1):37-46.

69. Gallegos, RP; Swingen, C; Wang, X; Bianco, RW; Jerosch-Herold, M; Bolman, R. M., 3rd.  Infarct extent by MRI corelates with peak serum troponin level in the canine model. Surg Research 2004; 118 (2)

70. Andrew L. Rivard, Robert P. Gallegos, Richard W. Bianco, Kenneth Liao, The Basis of Donor Heart Preservation (A Review), Journal of Extra-Corporeal Technology, Sep;36(3):269-74, 2004.

71. Andrew L. Rivard, Cory M. Swingen, Robert P. Gallegos, Richard W. Bianco, & Michael Jerosch-Herold, Cardiac MRI in the Isolated Porcine Heart Reveals Possible Etiology of Sudden Right Heart Failure Following Heart Transplantation. International Journal of Cardiovascular Imaging; 2004 Vol. 20(5) 411-464

72. Clark JN, Ogle MF, Ashworth P, Bianco RW, Levy RJ. Prevention of calcification of bioprosthetic heart valve cusp and aortic wall with ethanol and aluminum chloride. Ann Thorac Surg. 2005 Mar;79(3):897-904.

73. Robert P. Gallegos, Pavel J. Nockel, Andrew L. Rivard, Richard W. Bianco, The Current State of In-vivo Pre-clinical Heart Valve Evaluation, J of Heart Valve Disease, May;14(3) 2005

74. Andrew L. Rivard, Barbara Sampson, Scott J. Crow, Richard W. Bianco. Leslie W. Miller, Preoperative predictors for postoperative problems in heart transplantation: psychiatric and psychosocial considerations. Progress in Transplantation 2005 Sept, 15 (3): 276-282

75. Rivard AL, Simura KJ, Mohammad S, Magembe AJ, Pearson HM, Hallman MR, Barnett SJ, Gallegos RP, Bianco RW, Rat intubation and ventilation for surgical research. J Invest Surg. 2006 Jul-Aug;19(4):267-74.

76. Andrew L. Rivard, Robert P. Gallegos, Richard W. Bianco, Clifford J. Steer, Betsy T. Kren, Cecilia M.P. Rodriguez, Walt C. Low, Absence of Apoptosis in Prolonged Storage of Hypothermic Isolated Porcine Hearts, (Submitted November 23th, 2004, Cardiovascular Pathology).

77. Andrew L. Rivard, Cory M. Swingen, Robert P. Gallegos, Daniel L. Gatlin, Michael Jerosch-Herold, Ranjit John, Richard W. Bianco, Evaluation of Perfusion and Viability in Hypothermic Non-beating Isolated Porcine Hearts using Cardiac MRI, (In Press, International Journal of Cardiovascular Imaging).

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Book Chapters:

1.  St.Cyr J, Ward H, Kriett J, Alyono D, Einzig S, Bianco R, Anderson R, Foker J.  Long term model for evaluation of myocardial metabolic recovery following global ischemia. In: Brautbar N. (ed) Myocardial and Skeletal Muscle Bioenergetics. New York, NY, Plenum Publishing, pp. 401-414, 1986.

2.  Association for the Advancement of Medical Instrumentation.  Cardiovascular implants Cardiac valve prostheses. ANSI/AAMI/ISO 5840-1996.  American National Standards Institute, Inc., 1997.

3. Bianco RW, Grehan JF, Svendsen CA.  Animal models in cardiovascular biomaterials testing.  Ratner B, Hoffman A, Schoen F, Lemons J (eds).  Biomaterials Science: An Introduction to Materials in Medicine. Academic Press, San Diego, CA., 1997

4. AAMI Vascular Prosthesis Committee – (Ricard Bianco-Member)  Cardiovascular Implants – Tubular Vascular Prostheses.  ANSI/AAMI/ISO 7198:1998-2001.  Association for the Advancement of Medical Instrumentation 2001, October 17

5. Bianco RW, Grehan JF, Grubbs BC, Mrachek JP, Schroeder EL, Schumacher CW, Svendsen CA.  Large Animal Models in Cardiac and Vascular Biomaterials Research and Testing..  Ratner B, Hoffman A, Schoen F, Lemons J (eds).  Biomaterials Science: An Introduction to Materials in Medicine. Academic Press, San Diego, CA., 2004

6. Gallegos, RP, Rivard AL, Bianco, RW. Animal Models for Cardiac Research in Handbook of Cardiac Anatomy, Physiology and Devices for the Biomedical Engineer, Iaizzo, PA, editor. Humana Press. 2004.

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